The Los Angeles Angels (62-90) and the Houston Astros (82-70) open a 4-game series on Thursday. First pitch from Minute Mark Park is scheduled for 8:10 p.m. ET. Let's check out BetMGM Sportsbook's MLB odds around the Angels vs Astros Opportunities and place your best bets with our expert MLB tips and predictions.

Season series: Astros lead 6-3

The Angels rebounded from an 8-4 loss to the Chicago White Sox on Monday to win their last two games by a combined score of 9-3. The under won both victories and the overall score in their last 6 games was 4-2.

The Astros lost 2 of 3 games in San Diego from Monday through Wednesday, but were able to secure a 3-game sweep of the Halos in Anaheim last weekend. All 3 wins were by 2 runs each. The under has won 5 of the last 6 games.

Expected starters for the Angels and Astros

LHP Jose Suarez against LHP Yusei Kikuchi

Suarez (1-2, 6.80 ERA) makes his 2nd start and 21st appearance. He has a WHIP of 1.70, 4.9 BB/9 and 9.8 K/9 in 42 1/3 IP.

• Last appearance: 4 IP, 0 ER, 5 H, 0 BB, 5 K in a 55-pitch relief appearance against the Astros on Friday
• Last start: Loss, 2 2/3 IP, 4 ER, 6 H (1 HR), 1 BB, 3 K in 9-4 road loss to Arizona Diamondbacks on June 11
• 2024 Road Splits: 1-2, 6.41 ERA, 19 2/3 IP, 14 ER, 3 HR, 1.58 WHIP, .247 opposing batting average (OBA), 13 BB, 22 K in 1 start (10 appearances)
• Career against Astros: 3-3, 4.20 ERA, 40 2/3 IP, 19 ER, 4 HR, 1.53 WHIP, 8.2 K/9 in 11 appearances (7 starts)

Kikuchi (9-9, 4.29 ERA) makes his 31st start. He has a WHIP of 1.22, 2.3 BB/9 and 10.4 K/9 in 163 2/3 IP.

• Last start: Win, 7 IP, 3 ER, 3 H (1 HR), 2 BB, 6 K in the 5-3 road win against the Angels on Friday
• 2024 Home Splits: 4-7, 4.30 ERA, 92 IP, 44 ER, 14 HR, 1.16 WHIP, .248 OBA, 19 BB, 108 K in 16 starts
• Last 7 games: 5-0, 3.19 ERA, 42 1/3 IP, 15 ER, 30 H, 8 BB, 48 K, 0.92 WHIP
• Career against the Angels: 2-4, 9.12 ERA, 49 1/3 IP, 50 ER, 18 HR, 18 BB, 48 K, 1.97 WHIP, 8.8 K/9 in 12 appearances (10 starts)

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Odds for Angels at Astros

Provided by BetMGM Sportsbook; visit the USA TODAY Sports Scores and Sports Betting Odds Hub for a complete list of MLB odds. Odds last updated at 12:33 a.m. ET.

• Moneyline (ML): Angels +220 (bet $100 to win $220) | Astros -275 (bet $275 to win $100)
• Running Line (RL)/Against the Spread (ATS): Angel +1.5 (+105) | Astros -1.5 (-125)
• Over/Under (O/U): 8 (O: -115 | U: -105)

Tips and predictions for the Angels at the Astros

forecast

Astros 6, Angels 4

Money line

The Astros (-275) will cost you nearly three times your potential winnings, and that's way too much risk for not nearly enough reward. Even as part of a multi-stakes parlay, including Houston sucks up all the value of your ticket.

Additionally, Houston is a risky bet against the left-handed Suarez, as the Astros have only a 21-21 record against left-handed starting pitchers, while the Angels have a 14-18 record against LHP this season.

HAPPEN.

Running Line/Against the Spread

The ASTROS -1.5 (-125) are a little cheaper on the run line. These teams just played in Anaheim over the weekend, with Houston not only winning each of the three games, but also winning each by exactly 2 runs. That includes a 5-3 win with Kikuchi on September 13th.

If you like Houston, you should be able to get a 2 or more run lead at home, but don't get too carried away.

Over/Under

OVER 8 (-115) is worth a look in this series opener.

The Astros are under 5-1 in their last 6 games, but all of those games have been on the road. The over is 6-1 in their last 7 games played at Minute Maid Park.

For the Halos, the Over has won their last 5 road games by a pace of 4-0-1. The Over has also scored in 2 of 3 games in the 1st Series in Houston from May 20-22.

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