One Direction star Liam Payne suffered a fractured skull and died instantly from “very serious injuries” when he suddenly fell from his third-floor hotel balcony in Argentina, medical officials said Thursday as they announced the singer's cause of death.

First responders had rushed to the CasaSur Palermo hotel in Buenos Aires after receiving a distress call from the distraught manager late Wednesday, but they could do nothing to save him, according to Alberto Crescenti, chief of Buenos Aires' emergency services.

“Our task was to go there quickly, provide medical assistance and try to revive him, but his injuries were incompatible with life,” the top doctor said, according to La Nacion.

“According to the team’s findings, there appears to have been a fractured skull and extremely serious injuries that resulted in his immediate death.”

He added: “The team could do absolutely nothing. There was no resuscitation as he was confirmed to have died. The whole body had very serious injuries.”

The 31-year-old Brit's cause of death was revealed shortly after the release of a 911 call from the hotel manager detailing the frightening moments that led to the singer's fatal fall – including saying that Payne had “put his life at risk”.

“Hello good morning. I just called and my line was disconnected. I'm calling (from) the CasaSur Hotel in Palermo, Costa Rica, 6032,” the manager was heard saying in Spanish in the audio.

The manager, “Esteban,” claimed that Payne had trashed his hotel room and was under the influence of “drugs and alcohol.”

“Well, we have a guest who is drunk on drugs and alcohol. And, well, he's… When he's conscious, he sets the whole room in turmoil. And, well, you need to send someone, please,” the manager told the dispatcher.

Police later confirmed that they had been called to the hotel after being informed of an “aggressive male who may be under the influence of drugs and alcohol.”

When police arrived, they discovered Payne's body in the hotel's courtyard after the manager reported hearing a loud noise coming from there.

The singer's body has since been sent for an autopsy, officials said.

With post wires